EP-1257: A look at pre-operative MRI accuracy at predicting rectal cancer staging post chemoradiotherapy

accuracy of mri in rectal cancer after preoperative neoadjuvant chemoradiotherapy

methods study on 34 patients diagnosed with rectal adenocarcinoma referred to oncology clinic was conducted. the treatment plan included 4050 cgy radiotherapy and 5fu, xeloda chemotherapy. all patients were assessed with 1/5 t mri 6 to 8 weeks after treatment. t1 and t2 images with sagittal, cronal and axial planes with and without contrast agent were obtained and interpreted by two radiologist...

Patterns of failure in patients with locally advanced rectal cancer receiving pre-operative or post-operative chemoradiotherapy

BACKGROUND We investigated patterns of failure in patients with locally advanced rectal cancer (LARC) according to chemoradiotherapy (CRT) timing: pre-operative versus post-operative. Also, patterns of failure, particularly distant metastasis (DM), were analyzed according to tumor location within the rectum. METHODS In total, 872 patients with LARC who had undergone concurrent CRT and radical...

Rectal cancer: MRI assessment and staging

Optimal Time Intervals between Pre-Operative Radiotherapy or Chemoradiotherapy and Surgery in Rectal Cancer?

BACKGROUND In rectal cancer therapy, radiotherapy or chemoradiotherapy (RT/CRT) is extensively used pre-operatively to (i) decrease local recurrence risks, (ii) allow radical surgery in non-resectable tumors, and (iii) increase the chances of sphincter-saving surgery or (iv) organ-preservation. There is a growing interest among clinicians and scientists to prolong the interval from the RT/CRT t...

Local excision following pre-operative chemoradiotherapy-induced downstaging for selected cT3 distal rectal cancer.

OBJECTIVE To investigate the long-term outcomes of selected patients with cT3 distal rectal cancer treated with local excision following pre-operative chemoradiotherapy. METHODS Between January 2003 and February 2008, 11 patients with cT3 distal rectal cancer received a local excision following pre-operative chemoradiotherapy. The median age of the patients was 61 years (range, 42-71). The me...